Accutane – What Is It Exactly?
Accutane, which is isotretinoin, – is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.
40 mg po daily for 2-4 weeks.
Starting at a lower dose decreases the potential of an acne flare and produces a less severe onset of side-effects such as dryness and it helps with compliance.
Occasionally a low initial dose such as 10mg a day can be used if the physician or patient are anxious about side effects.
1mg/per kg per day can be used after 2-4 weeks bearing in mind that the caps are 10mg and 40 mg each.
The most common dose is 40mg alternating with 80 mg per day for the averaged sized person and 80mg -120 mg for larger patients.